The capacity of blood to form a fibrin clot by means of the extrinsic hemostatic pathway requires thromboplastin, calcium, factors I, II, V, VII and X(4,5). The PT-HS reagent provides a source of tissue thromboplastin and calcium that specifically activates factor VII in the extrinsic coagulation pathway. The factors involved in the intrinsic coagulation pathway are bypassed6. Therefore, deficiencies of intrinsic pathway factors (VIII, IX and XII) are not detected using the PT test.
Reagent Composition
PT-HS
DIL
PT Diluent
Optative.
Storage and Stability
Store at 2-8ºC.
The reagents are stable until the expiry date stated on the label. The reconstituted PT-HS reagent is stable for 8 hours at 37ºC or 12 days at 2-8ºC, 1 day at 20-25ºC or 5 days at 15-19ºC stored in the original container. Do not freeze.
Storage and Stability
Store at 2-8ºC.
The reagents are stable until the expiry date stated on the label. The reconstituted PT-HS reagent is stable for 8 hours at 37ºC or 12 days at 2-8ºC, 1 day at 20-25ºC or 5 days at 15-19ºC stored in the original container. Do not freeze.
